This textbook from Vallabh Prakashan is an English medium (अंग्रेजी माध्यम) book on Physical Pharmaceutics, written by CVS Subrahmanyam, prepared for B.Pharm students as per the PCI syllabus, and also used by M.Pharm students, research scholars and industry trainees working on formulation development. The book explains the physical chemistry that underlies every dosage form — why a drug dissolves at the rate it does, why a suspension settles, why an emulsion cracks, why a tablet flows or fails to flow through a hopper, and how long a product will remain within specification — so that formulation is treated as applied physicochemistry (भौतिक-रासायनिक सिद्धांत) rather than as a set of recipes. The book covers states of matter and phase equilibria, physicochemical properties of drug molecules, solubility and distribution phenomena, ionic equilibria, buffers and isotonic solutions, complexation and protein binding, diffusion and dissolution, kinetics and drug stability with accelerated stability testing and shelf-life determination, interfacial and surface phenomena including surfactants and adsorption, colloidal dispersions, coarse dispersions covering suspensions and emulsions, rheology and flow properties, micromeritics and particle-size analysis, thermodynamics and its pharmaceutical applications, and preformulation studies. Its distinguishing feature is the quantitative treatment — derivations set out step by step and worked numerical problems given throughout, supported by diagrams and tables. All content, terminology and explanations in this book are presented in the English language only.
Key Features:
English medium book — complete content, terminology and explanations in English
Written by CVS Subrahmanyam, published by Vallabh Prakashan
Standard textbook for B.Pharm students as per the PCI syllabus
Also useful for M.Pharm students, research scholars and formulation trainees
Physicochemical principles applied directly to dosage form design
Derivations set out step by step for clear understanding
Worked numerical problems given throughout
Diagrams, graphs and tables for quick visual learning
Chapter-end questions for revision and examination practice
States of matter, phase equilibria and phase rule
Physicochemical properties of drug molecules
Solubility and distribution phenomena
Ionic equilibria, buffers, pH and isotonic solutions
Complexation and protein binding
Diffusion, dissolution and drug release
Chemical kinetics, drug stability and shelf-life determination
Accelerated stability testing and expiry date calculation
Interfacial and surface phenomena, surfactants and adsorption
Colloidal dispersions and their pharmaceutical applications
Coarse dispersions — suspensions and emulsions
Rheology, flow properties and viscosity measurement
Micromeritics and particle-size analysis
Thermodynamics and its pharmaceutical applications
Preformulation studies in product development
Useful for B.Pharm and M.Pharm university examinations, practicals and viva voce preparation
B.Pharm विद्यार्थियों के लिए Vallabh Prakashan द्वारा प्रकाशित यह "Textbook of Physical Pharmaceutics" पुस्तक CVS Subrahmanyam द्वारा लिखी गई है तथा PCI पाठ्यक्रम के अनुसार है; यह M.Pharm विद्यार्थियों, शोधार्थियों एवं formulation से जुड़े प्रशिक्षुओं के लिए भी उपयोगी है। इसमें states of matter एवं phase equilibria, औषधि अणुओं के भौतिक-रासायनिक गुण, solubility एवं distribution, ionic equilibria, buffers व isotonic solutions, complexation, diffusion एवं dissolution, chemical kinetics एवं drug stability, surface phenomena एवं surfactants, colloidal व coarse dispersions (suspensions एवं emulsions), rheology, micromeritics, thermodynamics तथा preformulation अध्ययनों को derivations, हल किए गए numerical problems, चित्रों एवं तालिकाओं सहित समझाया गया है। सम्पूर्ण पुस्तक अंग्रेजी माध्यम (English medium) में है, इसमें हिंदी माध्यम की सामग्री सम्मिलित नहीं है।